Skeletal muscle-specific Sidt2 knockout in mice induced muscular dystrophy-like phenotype.

Huan Liu,Wenjun Jiang,Xueru Chen,Guoying Chang,Lei Zhao,Xihua Li,Huiwen Zhang

Metabolism（2018）

引用 14|浏览18

暂无评分

摘要

•Sidt2 is an integral lysosomal membrane protein.•Sidt2 deficiency in skeletal muscle results in pathognomonic hallmarks of muscular dystrophy.•LC3-II, p62, ubiquitinated aggregates and Lamp2-positive vacuoles were increased significantly in Sidt2-defiecient skeletal muscle fibers.

查看译文

关键词

α-GPD,ACP,AMP,β-gal,CK,H&E,GAA,GAPDH,GBA,GC,MGT,PAS,SOL,TA

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要