Lipoxin A4 inhibits UV radiation-induced skin inflammation and oxidative stress in mice

Journal of Dermatological Science(2018)

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摘要
•Lipoxin A4 protects mice skin from UV radiation. .•Lipoxin A4 inhibits UV-induced skin inflammation and oxidative stress.•Lipoxin A4 inhibits UV-induced pro-inflammatory cytokine production.•Lipoxin A4 induces anti-inflammatory IL-10 and TGF-β production.•Lipoxin A4 inhibits UV-induced oxidative stress and induces endogenous antioxidants.
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关键词
Lipid mediator,Ultraviolet radiation,Resolution of inflammation,Oxidative stress,Skin damage
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