Design, Synthesis, Structure-Activity Relationships and X-ray Structural Studies of Novel 1-Oxopyrimido[4,5-c]quinoline-2-acetic Acid Derivatives As Selective and Potent Inhibitors of Human Aldose Reductase.
European Journal of Medicinal Chemistry(2018)
Key words
1-Oxopyrimido[4,5-c]quinoline-2-acetic acids,AKR1B1,AKRIB10,Molecular modeling,X-ray crystallography
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