'Impact of an Additional Chromosome on the Clinical Outcomes of Hematopoietic Stem Cell Transplantation in Philadelphia Chromosome-Positive Acute Myeloid Leukemia in Adults'.

Biology of Blood and Marrow Transplantation(2018)

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摘要
•Philadelphia chromosome–positive AML patients can benefit from TKI interim therapy along with standard chemotherapy to achieve complete remission.•Minimal residual disease negativity could be a predictor of better clinical outcome after allogeneic hematopoietic cell transplantation.•The presence of inv(16) in patients with Ph+ AML is associated with better survival outcome.
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关键词
Acute myeloid leukemia,Philadelphia chromosome,Imatinib,inv(16),t(9,22)
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