'Impact of an Additional Chromosome on the Clinical Outcomes of Hematopoietic Stem Cell Transplantation in Philadelphia Chromosome-Positive Acute Myeloid Leukemia in Adults'.
Biology of Blood and Marrow Transplantation(2018)
摘要
•Philadelphia chromosome–positive AML patients can benefit from TKI interim therapy along with standard chemotherapy to achieve complete remission.•Minimal residual disease negativity could be a predictor of better clinical outcome after allogeneic hematopoietic cell transplantation.•The presence of inv(16) in patients with Ph+ AML is associated with better survival outcome.
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关键词
Acute myeloid leukemia,Philadelphia chromosome,Imatinib,inv(16),t(9,22)
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