Tumour-associated macrophages: Relation with progression and invasiveness, and assessment of M1/M2 macrophages in canine mammary tumours.

L N Monteiro,M A Rodrigues,D A Gomes,B S Salgado,G D Cassali

The Veterinary Journal（2018）

引用 33|浏览6

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摘要

•Tumour-associated macrophage (TAM) counts are higher in more aggressive histotypes of canine mammary tumors (CMTs).•TAM counts are related to various clinicopathological parameters and overall survival in CMTs.•Macrophages subpopulations are predominantly of M1 type in benign CMTs and of M2 type in malignant CMTs.

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关键词

Canine,Inflammation,Mammary tumour,Tumour-associated macrophages,Tumour microenvironment

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