Clinical and analytical evaluation of the new Aptima Mycoplasma genitalium assay, with data on M. genitalium prevalence and antimicrobial resistance in M. genitalium in Denmark, Norway and Sweden in 2016.

M Unemo, K Salado-Rasmussen, M Hansen,A O Olsen,M Falk,D Golparian, M Aasterød, J Ringlander, C Stezckó Nilsson, M Sundqvist,K Schønning,H Moi,H Westh,J S Jensen

Clinical Microbiology and Infection（2018）

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摘要

Both transcription-mediated amplification (TMA)-based MG assays had a highly superior sensitivity compared to the mgpB qPCR. The prevalence of MG and azithromycin resistance was high. Validated and quality-assured molecular tests for MG, routine resistance testing of MG-positive samples and antimicrobial resistance surveillance are crucial.

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关键词

16S rRNA,23S rRNA,Antimicrobial resistance,Aptima,Azithromycin,Hologic,Moxifloxacin,Mycoplasma genitalium,parC

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