A Hen in the Wolf Den: A Pathobiont Tale

Matteo M. Guerrini,Alexis Vogelzang,Sidonia Fagarasan

Immunity（2018）

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摘要

Disruption of the gut microbiota is thought to contribute to disease onset in individuals with a genetic predisposition to autoimmunity. In a recent issue of Science, Manfredo Vieira et al. (2018) identify translocation of the gut commensal Enterococcus gallinarum into the liver as a trigger for the autoimmune disease systemic lupus erythematous.

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