A systematic and prospectively validated approach for identifying synergistic drug combinations against malaria.
Malaria journal（2018）
摘要
Systematic approaches can play an important role in accelerating discovering novel combinational therapies for malaria as it enables selecting novel synergistic compound pairs in a more informed and cost-effective manner.
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关键词
Compound combination modelling,Machine learning,Malaria,Synergistic anti-malaria compound combinations,Synergy prediction,Transcriptional drug repositioning
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