IL-17-producing ST2 + group 2 innate lymphoid cells play a pathogenic role in lung inflammation.

Ting Cai,Jinxin Qiu, Yan Ji,Wenjing Li,Zhaoyun Ding,Caixia Suo,Jiali Chang,Jingjing Wang,Rui He,Youcun Qian,Xiaohuan Guo,Liang Zhou,Huiming Sheng,Lei Shen,Ju Qiu

Journal of Allergy and Clinical Immunology（2019）

引用 100|浏览23

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摘要

During lung inflammation, IL-33 and leukotrienes synergistically induce ILC2s. ILC2s are highly pathogenic and unexpected source for IL-17 in lung inflammation.

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关键词

Asthma,group 2 innate lymphoid cells,IL-17

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