Induced hypothermia is associated with reduced circulating subunits of mitochondrial DNA in cardiac arrest patients

    Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis, Volume 29, Issue 4, 2018, Pages 525-528.

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    Keywords:
    DNA mitochondrial/bloodHypothermiacardiopulmonary resuscitationout of hospital cardiac arrest/therapy

    Abstract:

    Induced hypothermia may protect from ischemia reperfusion injury. The mechanism of protection is not fully understood and may include an effect on mitochondria. Here we describe the effect of hypothermia on circulating mitochondrial (mt) DNA in a substudy of a multicenter randomized trial (the Target Temperature Management trial). Circula...More

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