Behcet'S Disease: Pulmonary Aneurysm Resolution With Oral Therapy And Hla B72 Allele Association

Clarissa de Albuquerque Botura,Luiz Eduardo Bersani-Amado, Antônio Rubens Zacarias-Júnior, Sueli Donizete Boreli, Naiene Gomes Gordo Stecca,Bruno Ambrósio da Rocha,Roberto Kenji Nakamura Cuman,Ciomar Aparecida Bersani-Amado

CLINICAL MEDICINE & RESEARCH(2018)

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摘要
We report the case of a woman who was diagnosed with a pulmonary artery aneurysm that was caused by Behcet's disease. The patient was initially diagnosed with community-acquired pneumonia and then pulmonary thromboembolism and aneurysm of the right pulmonary artery segmental branch was confirmed. The initial treatment consisted of anticoagulant drugs. After analysis of the family history and a positive pathergy test, the patient was diagnosed with Behcet's disease. Oral pharmacological treatment began with corticosteroids, cyclophosphamide, and anticoagulant suspension. The HLA B72 allele was identified in the patient and her two sisters, demonstrating the familial characteristic of the disease and the presence of this allele in a female patient with Behcet's disease. After 12 months of treatment, the clinical condition completely resolved.
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关键词
Behcet's disease, Pulmonary artery aneurysm, HLA B72
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