Increased Prostate Cancer Glucose Metabolism Detected by 18 F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Localised Gleason 8-10 Prostate Cancers Identifies Very High-risk Patients for Early Recurrence and Resistance to Castration.

Etienne Lavallée,Michelle Bergeron,François-Alexandre Buteau,Annie-Claude Blouin,Nicolas Duchesnay,Thierry Dujardin,Rabi Tiguert,Louis Lacombe,Vincent Fradet,Molière Makao-Nguile,Yves Fradet,Jean-Mathieu Beauregard,Frédéric Pouliot

European Urology Focus（2019）

引用 25|浏览8

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摘要

In Gleason 8–10 prostate cancers, intraprostatic 18F-fluorodeoxyglucose uptake can discriminate, before local therapy, patients at risk of treatment failure and castration resistance. These patients might benefit from upfront adjuvant systemic therapies.

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关键词

High-grade prostate cancer,18F-fluorodeoxyglucose,Positron emission tomography,High-risk prostate cancer,Failure to local therapies,Castration resistance

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