Switching Therapy From Intravenous Landiolol To Transdermal Bisoprolol In A Patient With Thyroid Storm Complicated By Decompensated Heart Failure And Gastrointestinal Dysfunction

Thyroid storm is a life-threatening disorder that remains a therapeutic challenge. Although beta-blockers are the mainstay for treatment, their use can be challenging in cases complicated by rapid atrial fibrillation and decompensated heart failure. We present a case of thyroid storm-associated atrial fibrillation and decompensated heart failure complicated by gastrointestinal dysfunction secondary to diffuse peritonitis that was successfully managed by a switching therapy, in which the continuous intravenous administration of landiolol was changed to bisoprolol via transdermal patch, in the acute phase treatment. This switching therapy may offer a promising therapeutic option for this potentially lethal disorder.