Effect Of Intranasal Mupirocin Prophylaxis On Methicillin-Resistant Staphylococcus Aureus Transmission And Invasive Staphylococcal Infections In A Neonatal Intensive Care Unit

Elizabeth H Ristagno,Kristina A Bryant, Lynette F Boland,Gordon G Stout,Alan D Junkins,Charles R Woods,John A Myers,Claudia M Espinosa

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY（2018）

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摘要

The use of monthly intranasal mupirocin was associated with a significant reduction in the rate of methicillin-resistant Staphylococcus aureus transmission and Staphylococcus aureus invasive infection in a large neonatal intensive care unit. Resistance to mupirocin emerged over time, but it was rare and was not associated with adverse clinical outcomes.Infect Control Hosp Epidemiol 2018;39:741-745

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