Production of Foot-and-mouth disease virus capsid proteins by the TEV protease.

Michael Puckette,Justin D Smith,Lindsay Gabbert,Christopher Schutta,José Barrera,Benjamin A Clark,John G Neilan,Max Rasmussen

Journal of Biotechnology（2018）

引用 4|浏览19

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摘要

•Use of FMDV 2A sequence to produce TEVpro and substrate from a single ORF.•TEVpro processes a modified FMDV P1 polypeptide to produce FMDV capsid proteins.•This system functioned in mammalian and bacterial cells.

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关键词

FMDV,ORF,3Cpro,TEVpro,VPs,VLPs,EM

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