Long-Standing Ulcerative Colitis May Trigger A Multilineage Cancerization Field

Matteo Fassan,Stefano Brignola,Giacomo Sarzo,Rocco Cappellesso,Massimo Rugge

INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY（2018）

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摘要

Longstanding/relapsing inflammation characterizing ulcerative colitis (UC) has been associated to an increased risk of colon mucosa neoplastic transformation. We describe the clinicopathological features of a UC-related poorly-differentiated neuroendocrine carcinoma coexisting with a conventional adenocarcinoma. This case supports UC as a multilineage cancerization field.

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关键词

neuroendocrine carcinoma, inflammatory bowel disease, ulcerative colitis

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