Anti biofilm effect of dihydromyricetin-loaded nanocapsules on urinary catheter infected by Pseudomonas aeruginosa.

Colloids and Surfaces B: Biointerfaces(2017)

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摘要
•Cationic nanocapsules containing Dihydromyricetin (NC-DMY) were produced.•NC-DMY demonstrated adequate physicochemical characteristics.•NC-DMY and free Dihydromyricetin demonstrated activity against Pseudomonas aeuginosa.•NC-DMY reduced the formation of biofilm on urinary catheters by about 70%.•NC-DMY may be used as a promising antimicrobial and antibiofilm formulation.
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关键词
Antimicrobial activity,Eudragit RS 100®,Polymeric nanoparticles,Stability study,DMY
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