Ataxia-telangiectasia mutated interactor regulates head and neck cancer metastasis via KRas expression.

Yue-Ju Li,Wei-Ting Lai,Cheng-Chi Chang,Mark Yen-Ping Kuo,Yi-Ting Deng,Cheng-Ning Yang,Shih-Jung Cheng,Tai-Sheng Wu,Szu-Ta Chen,Been-Ren Lin

Oral Oncology（2017）

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摘要

•ATMIN is highly expressed in late-stage HNSCC patients’ tumors.•Knock-down of ATMIN in HNSCC cell line reduces the ability of lymph-node metastasis.•KRas is firstly identified as a ATMIN’s downstream target and an oncogene in HNSCC.

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HNSCC,ATMIN

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