The effect of n-3 fatty acids and coenzyme Q10 supplementation on neutrophil leukotrienes, mediators of inflammation resolution and myeloperoxidase in chronic kidney disease.

Anne E Barden,Sujata Shinde,Valerie Burke,Ian B Puddey,Lawrence J Beilin,Ashley B Irish,Gerald F Watts,Trevor A Mori

Prostaglandins & Other Lipid Mediators（2018）

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摘要

•n-3 FA supplementation increased neutrophil LTB5.•n-3 FA increased neutrophil 18-HEPE, and E-series resolvins derived from EPA.•n-3 FA increased neutrophil 17-HDHA and resolvin D5 derived from DHA.•n-3 FA supplementation reduced plasma myeloperoxidase.

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关键词

Leukotrienes,n-3 fatty acids,Myeloperoxidase,Specialised proresolving lipid mediators,Neutrophils

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