Adherent agarose mold cultures: an in vitro platform for multi-factorial assessment of passaged chondrocyte redifferentiation

Justin Parreno
Justin Parreno
Vanessa J Bianchi
Vanessa J Bianchi
Corey Sermer
Corey Sermer
Suresh C Regmi
Suresh C Regmi
Kandel
Kandel

Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2018.

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Keywords:
agarose mold culturebioengineeredcartilagechondrocytededifferentiationMore(1+)

Abstract:

Generating the best possible bioengineered cartilage from passaged chondrocytes requires culture condition optimization. In this study the use of adherent agarose mold (adAM) cultures to support redifferentiation of passaged twice (P2) chondrocytes and serve as a scalable platform to assess the effect of growth factor combinations on prot...More

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