Arterial stiffness and left ventricular performance in elderly patients with persistent atrial fibrillation

Aging clinical and experimental research(2018)

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摘要
Background The prevalence of atrial fibrillation (AF) and arterial stiffness (AS) increases with age. Aims To evaluate if AS is correlated to longitudinal strain (LS), a marker of left ventricular (LV) function, in elderly AF patients with preserved ejection fraction (EF) undergoing external cardioversion. Methods AS was measured using the cardio-ankle vascular index (CAVI), LS was calculated from echocardiographic data of three consecutive cardiac cycles. Results We enrolled 38 patients (age 76 ± 8 years; men 60.5%; EF 65 ± 7%). LS and CAVI were, respectively, − 17.7 ± 3.7% and 9.7 ± 1.3. Multivariate analysis showed that LV performance was inversely related to height ( p < 0.001) and to the presence of AF-related symptoms ( p = 0.008). LS grew with increasing values of CAVI ( p = 0.038). Conclusions In elderly AF patients with preserved systolic function, LV performance is directly associated with AS. This link could influence atrium remodeling and the incidence of arrhythmia relapse.
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关键词
Arterial stiffness,Atrial fibrillation,CAVI,Elderly,Electric cardioversion,Longitudinal strain
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