Expression of ATF6 as a marker of pre-cancerous atypical change in ulcerative colitis-associated colorectal cancer: a potential role in the management of dysplasia.

Marie Hanaoka,Toshiaki Ishikawa,Megumi Ishiguro,Michiyo Tokura,Shinichi Yamauchi,Akifumi Kikuchi,Hiroyuki Uetake,Masamichi Yasuno,Tatsuyuki Kawano

Journal of gastroenterology（2018）

引用 34|浏览26

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摘要

ATF6 was expressed in lesions undergoing pre-cancerous atypical change in both non-UC and UC-associated CRC and may be used to distinguish LGD from inflammatory regenerative epithelium in UC patients.

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关键词

ATF6,Colorectal cancer,Dysplasia,Ulcerative colitis,Unfolded protein response

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