RNA fusions involving CD28 are rare in peripheral T-Cell lymphomas and concentrate mainly in those derived from follicular helper T cells.

David Vallois,Aurélie Dupuy,Francois Lemonnier, George Allen,Edoardo Missiaglia,Virginie Fataccioli,Nicolas Ortonne,Aline Clavert,Richard Delarue,Marie-Christine Rousselet,Bettina Fabiani,Francisco Llamas-Gutierrez,Seishi Ogawa,Margot Thome,Young Hyeh Ko,Keisuke Kataoka,Philippe Gaulard,Laurence de Leval

HAEMATOLOGICA（2018）

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摘要

Peripheral T-cell lymphomas (PTCL) comprise usually aggressive neoplasms of mature T cells with a heterogeneous molecular background. Over the past years, several genomic studies stemming from different research groups have shown evidence that mutation-induced activation of the T-cell receptor (TCR

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关键词

Aggressive Non-Hodgkin's Lymphoma,Angioimmunoblastic T-cells lymphoma,CD28 fusions,Peripheral T-cells Lymphomas

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