Pros and Cons of Different Therapeutic Antibody Formats for Recombinant Antivenom Development

Andreas H. Laustsen,Jose Maria Gutierrez,Cecilie Knudsen,Kristoffer H. Johansen,Erick Bermudez-Mendez,Felipe A. Cerni,Jonas A. Jurgensen,Line Ledsgaard,Andrea Martos-Esteban,Mia Ohlenschlaeger,Urska Pus,Mikael R. Andersen,Bruno Lomonte,Mikael Engmark,Manuela B. Pucca

Toxicon（2018）

Cited 135|Views21

Key words

Antivenom,Venom,Recombinant antivenom,Antibodies,Snakebite,Scorpion sting,Spider bite,Animal envenoming,Pharmacokinetics,Pharmacodynamics,Immunogenicity,Venom neutralization,Antibody expression,Antivenom design,Adverse reactions,Neglected tropical diseases,Biotechnology

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