Mri Of Psoriatic Nail Disease Pre- And Post-Tnf Inhibitor Therapy Shows Persistent Subclinical Inflammation After 6 Months Despite Good Clinical Response

RMD OPEN(2018)

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摘要
### Key messages#### What is already known about this subject?#### What does this study add?#### How might this impact on clinical practice?Nail involvement is part of the clinical spectrum of psoriatic disease and is microanatomically associated with distal interphalangeal joint (DIPJ) entheses.1 Tumour necrosis factor (TNF) inhibitors have shown efficacy for psoriasis, arthritis, enthesitis, dactylitis and nail disease.2 Given the intimate links between psoriatic arthritis (PsA) and nail disease, it might be expected that nail disease improvement would be associated with resolution of the underlying arthropathic features.All participants gave written consent. All cases fulfilled the Classification Criteria for Psoriatic Arthritis (CASPAR) criteria for PsA.3 All cases were due to …
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关键词
inflammation,magnetic resonance imaging,psoriatic arthritis
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