Let me in: Control of HIV nuclear entry at the nuclear envelope.

Anvita Bhargava,Xavier Lahaye,Nicolas Manel

Cytokine & Growth Factor Reviews（2018）

引用 32|浏览9

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摘要

•HIV can enter the nucleus of non-dividing target cells such as lymphocytes, macrophages and dendritic cells.•Multiple viral and host factors control HIV entry into the nucleus.•Understanding the process of HIV entry into the nucleus will provide new targets for antiviral strategies.

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关键词

HIV,T cells,Macrophages,Dendritic cells,Nuclear import,Nuclear envelope,SUN,LINC complex,MX2,Interferon-stimulated genes,Innate immunity

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