A safety and immunogenicity study of immunization with hVEGF/RFASE in cynomolgus monkeys.

Madelon Q Wentink,Henk M W Verheul,Arjan W Griffioen,Kenneth A Schafer, Susan McPherson, Richard J Early,Hans J van der Vliet,Tanja D de Gruijl

Vaccine（2018）

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摘要

These data show that hVEGF/RFASE can be safely administered in cynomolgus monkeys, induces the desired immune response and therefore support the clinical development of this vaccine.

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关键词

VEGF,Vaccine,Angiogenesis,Antibodies,Cynomolgus monkeys

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