Thymoquinone Induces Apoptosis in B16-F10 Melanoma Cell Through Inhibition of p-STAT3 and Inhibits Tumor Growth in a Murine Intracerebral Melanoma Model

Mustafa Aziz Hatiboglu,Abdurrahim Kocyigit,Eray Metin Guler,Kerime Akdur,Arife Nalli,Ersin Karatas,Saffet Tuzgen

WORLD NEUROSURGERY（2018）

引用 29|浏览7

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摘要

•Thymoquinone exerts effective treatment against melanoma both in vitro and in vivo.•Survival increased by thymoquinone in a murine intracerebral melanoma model.•Thymoquinone enhanced apoptosis in melanoma cells through inhibition of p-STAT3.

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关键词

Apoptosis,Murine melanoma model,p-STAT3,Thymoquinone

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