Intermediate prognosis in metastatic germ cell tumours-outcome and prognostic factors.
European Journal of Cancer(2018)
摘要
•Outcome of patients with intermediate prognosis improved and is currently associated with a 5-year overall survival rate of 89%.•In case of refractory disease current patients received more frequently high-dose chemotherapy and treatment beyond second line.•Lactate dehydrogenase cut-off value of 2 upper limit of normal and alpha-fetoprotein levels of 6200 IU/ml pre-chemotherapy were prognosticators.•Trials with de-intensification of chemotherapy for some IPGCT patients are warranted.
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关键词
IGCCCG classification,Intermediate prognosis,Outcome,Prognostic factors
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