Risk management decisions in women with BRCA1 and BRCA2 mutations.

Rosemary Morgan,Audrey Brown,Kelly Jo Hamman,Jone Sampson,Arpana Naik,Kristen Massimino

The American Journal of Surgery（2018）

引用 9|浏览22

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摘要

•Majority of women with BRCA1/2 mutation chose surveillance over risk reducing mastectomy.•Rate of risk reducing mastectomy was similar among women with pathogenic BRCA1/2 mutation and VUS.•No woman with VUS underwent risk reducing mastectomy in the absence of breast cancer.

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关键词

Breast cancer,Genetic testing,BRCA,Variants of uncertain significance

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