Phase-encoded xSPEN: A novel high-resolution volumetric alternative to RARE MRI.
MAGNETIC RESONANCE IN MEDICINE(2018)
摘要
Purpose: To develop a rapid, non-CPMG high-resolution volumetric imaging approach, exhibiting a speed and in-plane resilience to field inhomogeneities comparable to RARE/turbo-spin-echo (TSE) while endowed with unique downsampling characteristics. Methods: A multi-scan extension of cross-term spatiotemporal encoding (xSPEN) is introduced and analyzed. The method simultaneously yields k(y)/k(z) data containing low and high frequency components, as well as transposed, low-resolution z/y images. This dual k-/spatial-domain information is captured by a multi-scan procedure that phase-encodes k(y) while simultaneously slice-selecting z. A reconstruction scheme converting this information into high resolution 3D images with fully multiplexed volumetric coverage is introduced and exemplified. Results: Phase-encoded xSPEN was tested by human brain imaging at sub-mm resolutions. The method exceeded 2D TSE's sensitivity by factors of approximate to 3-4, while providing similar resolution and SNR as 3D TSE in approximate to 50% acquisition times. The method's contrast is dominated by T-2 and is free from "bright-fat" effects associated to spin-echo trains. Further acceleration is enabled by the method's downsampling abilities. Tradeoffs between encoding time, number of measurements, spatial resolution, SNR, and artifact levels are also laid out. Conclusion: A new MRI strategy is introduced delivering high in-and through-plane resolutions while enjoying full Fourier multiplexing, leading to fast acquisitions with high SNR.
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关键词
cross-term spatiotemporal encoding,downsampling,high definition resolution enhancement,3D MRI,turbo spin-echo
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