Reduced nuclear translocation of serum response factor is associated with skeletal muscle atrophy in a cigarette smoke-induced mouse model of COPDWOS

    Ran Ma
    Ran Ma
    Xuefang Gong
    Xuefang Gong
    Hua Jiang
    Hua Jiang
    Chunyi Lin
    Chunyi Lin
    Xiaoming Xu
    Xiaoming Xu
    Cited by: 7|Bibtex|13|

    International journal of chronic obstructive pulmonary disease, Volume 122017, Pages 581-587.

    Keywords:
    SRFchronic obstructive pulmonary diseasecigarette smokingskeletal muscle atrophy

    Abstract:

    Skeletal muscle atrophy and dysfunction are common complications in the chronic obstructive pulmonary disease (COPD). However, the underlying molecular mechanism remains elusive. Serum response factor (SRF) is a transcription factor which is critical in myocyte differentiation and growth. In this study, we established a mouse COPD model i...More
    Your rating :
    0

     

    Tags
    Comments