Reduced nuclear translocation of serum response factor is associated with skeletal muscle atrophy in a cigarette smoke-induced mouse model of COPDWOS
International journal of chronic obstructive pulmonary disease, Volume 122017, Pages 581-587.
Keywords:SRFchronic obstructive pulmonary diseasecigarette smokingskeletal muscle atrophy
Skeletal muscle atrophy and dysfunction are common complications in the chronic obstructive pulmonary disease (COPD). However, the underlying molecular mechanism remains elusive. Serum response factor (SRF) is a transcription factor which is critical in myocyte differentiation and growth. In this study, we established a mouse COPD model i...More