Interferon α subtypes in HIV infection.

Cytokine & Growth Factor Reviews（2018）

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摘要

•The type I IFN family consists of 12 different IFNα subtypes with high sequence homology.•A specific IFNA subtype expression pattern is induced during HIV and SIV infection.•IFNα subtypes strongly differ in their antiviral and immunomodulatory effects against HIV.

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AIDS,APOBEC3G,ART,BLT,Dpi,HIV,IDO,IFITM,IFN,IFNAR,IRF,ISG,ISGF3,ISRE,LPMC,MAP,MHC,Mx2,NK cells,PBMC,pDC,PKR,rh,SAMHD1,SIV,STAT,TRAIL,Trim

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