Impact of high-flux haemodialysis on the probability of target attainment for oral amoxicillin/clavulanic acid combination therapy.

Katrina Hui,Kashyap Patel,David C M Kong,Carl M J Kirkpatrick

International Journal of Antimicrobial Agents（2017）

引用 3|浏览5

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摘要

•Effect of high-flux haemodialysis on amoxicillin/clavulanic acid (AMC) efficacy is unknown.•Once-daily dosing of AMC may result in insufficient exposures of clavulanic acid.•Once-daily dosing of AMC on dialysis days should be avoided.

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关键词

Antibiotics,Amoxicillin/clavulanic acid,Haemodialysis,Monte Carlo simulation

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