The Unusual Genetics and Biochemistry of Bovine Immunoglobulins

    Advances in immunology, Volume 137, 2018, Pages 135-164.

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    Keywords:
    AntibodyAntibody diversityAntibody repertoireBovine immunoglobulinCow antibodyMore(5+)

    Abstract:

    Antibodies are the key circulating molecules that have evolved to fight infection by the adaptive immune system of vertebrates. Typical antibodies of most species contain six complementarity-determining regions (CDRs), where the third CDR of the heavy chain (CDR H3) has the greatest diversity and often makes the most significant contact w...More

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