Generation of a human iPSC line from a patient with congenital glaucoma caused by mutation in CYP1B1 gene

Arantxa Bolinches-Amorós,Dunja Lukovic,Ana Artero Castro,Marian León,Kunka Kamenarova,Radka Kaneva,Pavla Jendelova,Fiona Blanco-Kelly,Carmen Ayuso,Marta Cortón,Slaven Erceg

Stem Cell Research（2018）

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摘要

The human iPSC cell line, GLC-FiPS4F1 (ESi047-A), derived from dermal fibroblast from the patient with congenital glaucoma caused by the mutation of the gene CYP1B1, was generated by non-integrative reprogramming technology using OCT3/4, SOX2, CMYC and KLF4 reprogramming factors.

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关键词

congenital glaucoma,human ipsc line,mutation,generation

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