Decreased medial prefrontal cortex activation during self-referential processing in bipolar mania

Dorrit Herold,Tatiana Usnich,Stephanie Spengler,Bastian Sajonz,Michael Bauer,Felix Bermpohl

Journal of Affective Disorders（2017）

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摘要

•Patients with mania show symptoms suggesting altered self-referential processing.•Activation of medial prefrontal cortex is decreased in patients with mania.•This finding reflects an opposite pattern to the findings in depression.

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关键词

Bipolar disorder,Mania,Self-referential processing,Medial prefrontal cortex,Functional magnetic resonance imaging

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