Patients treated with oxaliplatin are at risk for thrombocytopenia caused by multiple drug-dependent antibodies.

Brian R Curtis,Yen-Michael S Hsu,Nikolai Podoltsev,Jill Lacy,Susanna Curtis,Michael S Samuel,Kristin Zutavern,Robert A DeSimone,Daniel W Bougie,Richard H Aster

Blood（2018）

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摘要

TO THE EDITOR:Drug-induced immune thrombocytopenia (DITP) is caused by drug-dependent platelet-reactive antibodies DDAbs) that induce platelet destruction when a drug is taken for which the antibody is specific.[1][1][⇓][2][⇓][3][⇓][4]-[5][5] The widely used cancer drug oxaliplatin is a

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