The protective effect of alpha-lipoic acid against brain ischemia and reperfusion injury via mTOR signaling pathway in rats.

Xinjie Gao,Wei Chen,Jinquan Li,Chao Shen,Ping Zhou,Xiaoming Che,Xiaomu Li,Rong Xie

Neuroscience Letters（2018）

引用 19|浏览8

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摘要

•ALA protects against brain I/R injury both in acute stage and long-term observation.•The mTOR pathway involves in the pathophysiological mechanism of brain I/R injury.•The protection of ALA against brain I/R injury depends on mTOR signaling pathway.

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关键词

ALA,dMCAo,I/R,OGD,Rapa

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