Effect of dietary n-3 polyunsaturated fatty acid rich fish oil on the endometrial prostaglandin production in the doe (Capra hircus).

Prostaglandins & Other Lipid Mediators(2018)

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摘要
•Fish oil rich in EPA and DHA was supplemented per oral for 8 weeks in the doe.•Endometrium was collected by laparohysterotomy on day 16 post-estrus.•Endometrial explant culture was done to study PG synthesis.•Fish oil inhibited basal and OXT and/or roIFNτ induced production of PGF2α and PGE2.•Downregulation of COX-2 transcripts was the reason behind decreased PG production.
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关键词
Endometrium,Goat,Gene expression,n-3 PUFA,Prostaglandin
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