The effect of levetiracetam on rat bone mineral density, bone structure and biochemical markers of bone metabolism.

Iva Karesova,Julius Simko,Sona Fekete,Eva Zimcikova,Jana Malakova,Helena Zivna,Ladislava Pavlikova,Vladimir Palicka

European Journal of Pharmacology（2018）

引用 9|浏览14

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摘要

Some data suggest that exposure to levetiracetam (LEV) might be associated with a risk for bone health in the model of orchidectomized rats. The aim of this study was to investigate if there is any significant risk of LEV for bone health in the model of gonadally intact animals.

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关键词

Antiepileptic drugs,Levetiracetam,Bone mineral density,Bone markers,Biomechanical properties

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