Identification of chronic myeloid leukemia patients treated with imatinib who are potentially eligible for treatment discontinuation by assessing real-life molecular responses on the international scale in a EUTOS-certified lab

Amélie Heinrichs, Barbara Dessars,Hakim El Housni, Wim Pluymers, Karen Peeters, Fleur S. Benghiat,Pierre Heimann

Leukemia Research(2018)

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摘要
•Real-life molecular responses on international scale in EUTOS-certified laboratory.•53.4% of patients were in deep molecular responses ≥MR4.5 at last visit.•36.2% of patients had ≥MR4.5 and were treated for >5.8 years; 26.7% for >8 years.•Potential patients for treatment-free remission attempt outside clinical trials were identified.
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CML,CML-CP,DMR,ELN,ENESTFreedom,ENESTop,EURO-SKI,EUTOS,IM,IRIS,IS,y,m,MMR,MR,RQ-PCR,SD,STIM,TFR,TKI,TWISTER,ULB
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