Successful Treatment of Human Plague with Oral Ciprofloxacin.

Titus Apangu,Kevin Griffith, Janet Abaru, Gordian Candini,Harriet Apio,Felix Okoth,Robert Okello,John Kaggwa,Sarah Acayo,Geoffrey Ezama,Brook Yockey,Christopher Sexton,Martin Schriefer,Edward Katongole Mbidde,Paul Mead

EMERGING INFECTIOUS DISEASES（2017）

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摘要

The US Food and Drug Administration recently approved ciprofloxacin for treatment of plague (Yersina pestis infection) based on animal studies. Published evidence of efficacy in humans is sparse. We report 5 cases of culture-confirmed human plague treated successfully with oral ciprofloxacin, including 1 case of pneumonic plague.

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FDA approval,Yersinia pestis,bacteria,bacterial infection,ciprofloxacin,human,infectious diseases,plague,treatment,vector-borne infections,zoonoses

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