Subclinical atherosclerosis in adults with steady-state bronchiectasis: A case-control study.

•This study represents the first study which directly evaluates the functional and structural vascular abnormalities in patients with clinically sable bronchiectasis.•We showed that FMD in bronchiectasis patients was markedly lower than in healthy subjects, and that FMD was mainly determined by the age, BMI, PA colonization and HRCT scores.•In addition, there were negative, significant correlations between FMD% and bronchiectasis severity metrics, including the BSI and FACED scores.•However, bronchiectasis patients and healthy subjects did not differ in CIMT.•Considering these vascular markers have been linked with cardiovascular risk in generals, our results highlight the need to call for the vigilance to screen early for vascular changes to minimize the future risks of cardiovascular events.