Basic fibroblast growth factor enhances cell proliferation in the dentate gyrus of neonatal rats following hypoxic-ischemic brain damage.

Huan Zhu,Lixing Qiao,Yao Sun,Liping Yin,Li Huang,Li Jiang,Jiaqing Li

Neuroscience Letters（2018）

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摘要

•Cell proliferation was induced by HIBD in hippocampal DG of neonatal rats.•bFGF gene expression was upregulated in hippocampus following HIBD in neonatal rats, especially between 7 and 14 days.•Intraperitoneally injection of exogenous bFGF enhanced cell proliferation in hippocampal DG following neonatal HIBD.

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关键词

Cell proliferation,Dentate gyrus,Neonatal HIBD,bFGF,Cerebral hypoxia,Cerebral ischemia

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