Natural immunity against capsular group X N. meningitidis following an outbreak in Togo, 2007.
Vaccine(2018)
摘要
•Serogroup X meningococci (MenX) has caused localized outbreaks in Africa in the last decade, and vaccines are in development.•To inform vaccine development we investigated the serum antibody responses against MenX in individuals living in an area affected by a MenX outbreak during 2007 in Togo, West Africa.•We found that dependent on age, 29–34% of Togolese study participants showed serum bactericidal antibody against the MenX strain; significantly higher than controls from the U.K. and Burkina Faso.
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关键词
Neisseria meningitidis,Meningococcal,Capsular group X,Polysaccharide,Bactericidal,Antibodies
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