Intrathecal trastuzumab in the management of HER2+ breast leptomeningeal disease: a single institution experience.

Nicholas B Figura,Wendy Long,Michael Yu,Timothy J Robinson,Sepideh Mokhtari,Arnold B Etame,Nam D Tran,Roberto Diaz,Hatem Soliman,Heather S Han,Solmaz Sahebjam,Peter A Forsyth,Kamran A Ahmed

Breast cancer research and treatment（2018）

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摘要

IT trastuzumab was well tolerated with prolongation of OS over historical controls. IT trastuzumab should be considered for management of HER2+ leptomeningeal disease patients.

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关键词

HER2+ breast cancer,Intrathecal herceptin,Intrathecal trastuzumab,Leptomeningeal disease

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