ATF3 is positively involved in particulate matter-induced airway inflammation in vitro and in vivo.

Fugui Yan,Yinfang Wu,Huiwen Liu,Yanping Wu,Huahao Shen,Wen Li

Toxicology Letters（2018）

引用 11|浏览14

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摘要

•PM significantly upregulated ATF3 expression in HBE cells and mouse lung tissues.•ATF3 has promoting effects in PM-induced airway inflammation in vitro an in vivo.•ATF3 mediated PM-induced inflammatory partly through NF-κB and AP-1 pathways.

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关键词

ATF3,Particulate matter,Inflammation,Airway epithelial cells,NF-κB,AP-1

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