Expression of hypoxia inducible factor-2 alpha in overloaded- stress induced destruction of mandibular condylar chondrocytes.

Wen Li,Yanhui Liu,Wanghui Ding,Tan Long,Jiejun Shi

Archives of Oral Biology（2017）

引用 6|浏览3

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摘要

•This is the first to study the expression of HIF-2α in condylar chondrocytes.•To investigate the possible effects of HIF-2α involved in the destruction of condylar chondrocytes by studying the protein expression of HIF-2α and it’s downstream catabolic factors (MMP3, MMP13, ADAMTS4) under the stress loading and hypoxic condition.

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关键词

HIF-2α,MMP3,MMP13,ADAMTS4,Condylar cartilage

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