Two weeks of variable stress increases gamma-H2AX levels in the mouse bed nucleus of the stria terminalis.

Brendan D Hare,Tina M Thornton,Mercedes Rincon, Borivoj Golijanin,S Bradley King,Diane M Jaworski,William A Falls

Neuroscience（2018）

引用 14|浏览21

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摘要

•Increased anxiety and γH2AX levels following 14 days of variable stress.•γH2AX levels and expression are associated with GSK3β ser389 phosphorylation.•Demonstrated effects are unique to prolonged stress experience.

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关键词

BNST,DSBs,GSK3β,MAPK,mPFC,PBS,γH2AX

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